BDBM50315982 3-(4-((1H-pyrazol-1-yl)methyl)-2-phenethoxyphenyl)-N-(3,4-difluorophenylsulfonyl)propanamide::CHEMBL1093820

SMILES: Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccccc1

InChI Key: InChIKey=ODDJYDFHXSKXHR-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50315982   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid EP3 Receptor (Mus musculus (Mouse))	BDBM50315982 (3-(4-((1H-pyrazol-1-yl)methyl)-2-phenethoxyphenyl)...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccccc1 Show InChI InChI=1S/C27H25F2N3O4S/c28-24-11-10-23(18-25(24)29)37(34,35)31-27(33)12-9-22-8-7-21(19-32-15-4-14-30-32)17-26(22)36-16-13-20-5-2-1-3-6-20/h1-8,10-11,14-15,17-18H,9,12-13,16,19H2,(H,31,33)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair
Prostanoid EP1 Receptor (Mus musculus (Mouse))	BDBM50315982 (3-(4-((1H-pyrazol-1-yl)methyl)-2-phenethoxyphenyl)...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccccc1 Show InChI InChI=1S/C27H25F2N3O4S/c28-24-11-10-23(18-25(24)29)37(34,35)31-27(33)12-9-22-8-7-21(19-32-15-4-14-30-32)17-26(22)36-16-13-20-5-2-1-3-6-20/h1-8,10-11,14-15,17-18H,9,12-13,16,19H2,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair
Prostanoid EP4 Receptor (Mus musculus (Mouse))	BDBM50315982 (3-(4-((1H-pyrazol-1-yl)methyl)-2-phenethoxyphenyl)...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccccc1 Show InChI InChI=1S/C27H25F2N3O4S/c28-24-11-10-23(18-25(24)29)37(34,35)31-27(33)12-9-22-8-7-21(19-32-15-4-14-30-32)17-26(22)36-16-13-20-5-2-1-3-6-20/h1-8,10-11,14-15,17-18H,9,12-13,16,19H2,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair
Prostanoid EP2 Receptor (Mus musculus (Mouse))	BDBM50315982 (3-(4-((1H-pyrazol-1-yl)methyl)-2-phenethoxyphenyl)...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccccc1 Show InChI InChI=1S/C27H25F2N3O4S/c28-24-11-10-23(18-25(24)29)37(34,35)31-27(33)12-9-22-8-7-21(19-32-15-4-14-30-32)17-26(22)36-16-13-20-5-2-1-3-6-20/h1-8,10-11,14-15,17-18H,9,12-13,16,19H2,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair
Prostanoid EP3 Receptor (Mus musculus (Mouse))	BDBM50315982 (3-(4-((1H-pyrazol-1-yl)methyl)-2-phenethoxyphenyl)...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccccc1 Show InChI InChI=1S/C27H25F2N3O4S/c28-24-11-10-23(18-25(24)29)37(34,35)31-27(33)12-9-22-8-7-21(19-32-15-4-14-30-32)17-26(22)36-16-13-20-5-2-1-3-6-20/h1-8,10-11,14-15,17-18H,9,12-13,16,19H2,(H,31,33)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level after...				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair