BDBM50316031 CHEMBL1090366::amino(phenyl)methylphosphonic acid
SMILES: NC(c1ccccc1)P(O)(O)=O
InChI Key: InChIKey=ZKFNOUUKULVDOB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human)) | BDBM50316031 (CHEMBL1090366 | amino(phenyl)methylphosphonic acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of Human MetAP1b using Met-pNA as substrate | J Med Chem 58: 2350-7 (2015) Article DOI: 10.1021/jm501790e BindingDB Entry DOI: 10.7270/Q2C53NJX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pyrroline-5-carboxylate reductase (Arabidopsis thaliana) | BDBM50316031 (CHEMBL1090366 | amino(phenyl)methylphosphonic acid) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.56E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara Curated by ChEMBL | Assay Description Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 min | J Agric Food Chem 56: 3193-9 (2008) Article DOI: 10.1021/jf800029t BindingDB Entry DOI: 10.7270/Q2N58Q73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyrroline-5-carboxylate reductase (Arabidopsis thaliana) | BDBM50316031 (CHEMBL1090366 | amino(phenyl)methylphosphonic acid) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.56E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara Curated by ChEMBL | Assay Description Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 min | J Agric Food Chem 56: 3193-9 (2008) Article DOI: 10.1021/jf800029t BindingDB Entry DOI: 10.7270/Q2N58Q73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aminopeptidase N (Sus scrofa (Pig)) | BDBM50316031 (CHEMBL1090366 | amino(phenyl)methylphosphonic acid) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate | Bioorg Med Chem 18: 2930-6 (2010) Article DOI: 10.1016/j.bmc.2010.02.056 BindingDB Entry DOI: 10.7270/Q2FN16C0 | |||||||||||
More data for this Ligand-Target Pair |