BDBM50316101 3-Methyl-2-[4'-(methylsulfonyl)biphenyl-3-yl]-5-(trifluoromethyl)quinoxaline::CHEMBL1093259

SMILES: Cc1nc2c(cccc2nc1-c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key: InChIKey=ZOAHFZQNTOTYOA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50316101 (3-Methyl-2-[4'-(methylsulfonyl)biphenyl-3-yl]-5-(t...) Show SMILES Cc1nc2c(cccc2nc1-c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-8-4-7-19(22(20)27-14)23(24,25)26)17-6-3-5-16(13-17)15-9-11-18(12-10-15)31(2,29)30/h3-13H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human LXRalpha ligand binding domain				J Med Chem 53: 3296-304 (2010) Article DOI: 10.1021/jm100034x BindingDB Entry DOI: 10.7270/Q29W0FN8
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50316101 (3-Methyl-2-[4'-(methylsulfonyl)biphenyl-3-yl]-5-(t...) Show SMILES Cc1nc2c(cccc2nc1-c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-8-4-7-19(22(20)27-14)23(24,25)26)17-6-3-5-16(13-17)15-9-11-18(12-10-15)31(2,29)30/h3-13H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human LXRbeta ligand binding domain				J Med Chem 53: 3296-304 (2010) Article DOI: 10.1021/jm100034x BindingDB Entry DOI: 10.7270/Q29W0FN8
					More data for this Ligand-Target Pair