BDBM50316126 Bleph-10::Bleph-30::Blephamide::CHEMBL455::Cetamide::Cetapred::FML-S::Klaron::Metimyd::N-Acetyl-4-amino-benzenesulfonamide::Ocusulf-10::Ocusulf-30::Predamide::Predsulfair::SULF-10::SULF-15::SULFACETAMIDE::Sulfacel-15::Sulfacetamide, 1::Sulfair-15::Sulphacetamide::Sulphrin::Sulster::Sulten-10::Vasocidin

SMILES: CC(=O)NS(=O)(=O)c1ccc(N)cc1

InChI Key: InChIKey=SKIVFJLNDNKQPD-UHFFFAOYSA-N

Data: 1 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50316126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human))	BDBM50316126 (Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...) Show SMILES CC(=O)NS(=O)(=O)c1ccc(N)cc1 Show InChI InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents	Article PubMed	8.60E+4	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Atatürk University					Assay Description The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...				Chem Biol Drug Des 76: 552-8 (2010) Article DOI: 10.1111/j.1747-0285.2010.01036.x BindingDB Entry DOI: 10.7270/Q2Q52N3T
					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM50316126 (Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...) Show SMILES CC(=O)NS(=O)(=O)c1ccc(N)cc1 Show InChI InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...				Drug Metab Dispos 40: 2332-41 (2012) Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M
					More data for this Ligand-Target Pair
Dihydrofolate reductase (DHFR) (Bos taurus (Cattle))	BDBM50316126 (Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...) Show SMILES CC(=O)NS(=O)(=O)c1ccc(N)cc1 Show InChI InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of bovine DHFR after 2 mins				Bioorg Med Chem 18: 2849-63 (2010) Article DOI: 10.1016/j.bmc.2010.03.019 BindingDB Entry DOI: 10.7270/Q2M61M6S
					More data for this Ligand-Target Pair
Multidrug and toxin extrusion protein 1 (Homo sapiens (Human))	BDBM50316126 (Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...) Show SMILES CC(=O)NS(=O)(=O)c1ccc(N)cc1 Show InChI InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay				J Med Chem 56: 781-95 (2013) Article DOI: 10.1021/jm301302s BindingDB Entry DOI: 10.7270/Q2F76DWZ
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Homo sapiens (Human))	BDBM50316126 (Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...) Show SMILES CC(=O)NS(=O)(=O)c1ccc(N)cc1 Show InChI InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of human DHFR after 2 mins				Bioorg Med Chem 18: 2849-63 (2010) Article DOI: 10.1016/j.bmc.2010.03.019 BindingDB Entry DOI: 10.7270/Q2M61M6S
					More data for this Ligand-Target Pair