BDBM50316199 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol::CHEMBL1098944

SMILES: CCn1c(nc2c(nc(OC[C@@H](C)N)cc12)C#CC(C)(C)O)-c1nonc1N

InChI Key: InChIKey=CGJRAACGTIIYDY-SNVBAGLBSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50316199 (4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-amino...) Show SMILES CCn1c(nc2c(nc(OC[C@@H](C)N)cc12)C#CC(C)(C)O)-c1nonc1N |r| Show InChI InChI=1S/C18H23N7O3/c1-5-25-12-8-13(27-9-10(2)19)21-11(6-7-18(3,4)26)14(12)22-17(25)15-16(20)24-28-23-15/h8,10,26H,5,9,19H2,1-4H3,(H2,20,24)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GSK3beta phosphorylation in human BT474 cells				Bioorg Med Chem Lett 19: 1508-11 (2009) Article DOI: 10.1016/j.bmcl.2009.01.002 BindingDB Entry DOI: 10.7270/Q2XK8FP7
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase AKT2 (Homo sapiens (Human))	BDBM50316199 (4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-amino...) Show SMILES CCn1c(nc2c(nc(OC[C@@H](C)N)cc12)C#CC(C)(C)O)-c1nonc1N |r| Show InChI InChI=1S/C18H23N7O3/c1-5-25-12-8-13(27-9-10(2)19)21-11(6-7-18(3,4)26)14(12)22-17(25)15-16(20)24-28-23-15/h8,10,26H,5,9,19H2,1-4H3,(H2,20,24)/t10-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT2				Bioorg Med Chem Lett 19: 1508-11 (2009) Article DOI: 10.1016/j.bmcl.2009.01.002 BindingDB Entry DOI: 10.7270/Q2XK8FP7
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50316199 (4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-amino...) Show SMILES CCn1c(nc2c(nc(OC[C@@H](C)N)cc12)C#CC(C)(C)O)-c1nonc1N |r| Show InChI InChI=1S/C18H23N7O3/c1-5-25-12-8-13(27-9-10(2)19)21-11(6-7-18(3,4)26)14(12)22-17(25)15-16(20)24-28-23-15/h8,10,26H,5,9,19H2,1-4H3,(H2,20,24)/t10-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT				Bioorg Med Chem Lett 19: 1508-11 (2009) Article DOI: 10.1016/j.bmcl.2009.01.002 BindingDB Entry DOI: 10.7270/Q2XK8FP7
					More data for this Ligand-Target Pair