BDBM50316273 3-(4-morpholino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)aniline::CHEMBL1097262

SMILES: Nc1cccc(c1)-c1nc(N2CCOCC2)c2cnn(-c3ccccc3)c2n1

InChI Key: InChIKey=DWESOYJSBBZUMD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50316273 (3-(4-morpholino-1-phenyl-1H-pyrazolo[3,4-d]pyrimid...) Show SMILES Nc1cccc(c1)-c1nc(N2CCOCC2)c2cnn(-c3ccccc3)c2n1 Show InChI InChI=1S/C21H20N6O/c22-16-6-4-5-15(13-16)19-24-20(26-9-11-28-12-10-26)18-14-23-27(21(18)25-19)17-7-2-1-3-8-17/h1-8,13-14H,9-12,22H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	436	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha by DELFIA assay				J Med Chem 52: 8010-24 (2009) Article DOI: 10.1021/jm9013828 BindingDB Entry DOI: 10.7270/Q28W3DGF
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50316273 (3-(4-morpholino-1-phenyl-1H-pyrazolo[3,4-d]pyrimid...) Show SMILES Nc1cccc(c1)-c1nc(N2CCOCC2)c2cnn(-c3ccccc3)c2n1 Show InChI InChI=1S/C21H20N6O/c22-16-6-4-5-15(13-16)19-24-20(26-9-11-28-12-10-26)18-14-23-27(21(18)25-19)17-7-2-1-3-8-17/h1-8,13-14H,9-12,22H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cells				J Med Chem 52: 8010-24 (2009) Article DOI: 10.1021/jm9013828 BindingDB Entry DOI: 10.7270/Q28W3DGF
					More data for this Ligand-Target Pair