BDBM50316312 ((2R,3S,4R,5R)-5-(2-Amino-7-(4-carboxybenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1095608

SMILES: Nc1nc2n(c[n+](Cc3ccc(cc3)C(O)=O)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O

InChI Key: InChIKey=IIPLIRRYNLPNLW-XNIJJKJLSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316312   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316312 (((2R,3S,4R,5R)-5-(2-Amino-7-(4-carboxybenzyl)-6-ox...) Show SMILES Nc1nc2n(c[n+](Cc3ccc(cc3)C(O)=O)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C18H20N5O10P/c19-18-20-14-11(15(26)21-18)22(5-8-1-3-9(4-2-8)17(27)28)7-23(14)16-13(25)12(24)10(33-16)6-32-34(29,30)31/h1-4,7,10,12-13,16,24-25H,5-6H2,(H5-,19,20,21,26,27,28,29,30,31)/t10-,12-,13-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.59E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
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