null

SMILES: CCn1cc(c(n1)-c1ccc(NC(=O)Nc2ccccc2)cc1)-c1ccnc2[nH]c(cc12)-c1ccc(CN(C)C)cc1C

InChI Key: InChIKey=LLGYBOCRDSLEKE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316508   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50316508 (4-[3-(4-N-Phenylcarbamylaminophenyl)-1-ethyl-1H-py...) Show SMILES CCn1cc(c(n1)-c1ccc(NC(=O)Nc2ccccc2)cc1)-c1ccnc2[nH]c(cc12)-c1ccc(CN(C)C)cc1C Show InChI InChI=1S/C35H35N7O/c1-5-42-22-31(33(40-42)25-12-14-27(15-13-25)38-35(43)37-26-9-7-6-8-10-26)29-17-18-36-34-30(29)20-32(39-34)28-16-11-24(19-23(28)2)21-41(3)4/h6-20,22H,5,21H2,1-4H3,(H,36,39)(H2,37,38,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human Aurora A				J Med Chem 53: 3973-4001 (2010) Article DOI: 10.1021/jm901870q BindingDB Entry DOI: 10.7270/Q27082CK
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50316508 (4-[3-(4-N-Phenylcarbamylaminophenyl)-1-ethyl-1H-py...) Show SMILES CCn1cc(c(n1)-c1ccc(NC(=O)Nc2ccccc2)cc1)-c1ccnc2[nH]c(cc12)-c1ccc(CN(C)C)cc1C Show InChI InChI=1S/C35H35N7O/c1-5-42-22-31(33(40-42)25-12-14-27(15-13-25)38-35(43)37-26-9-7-6-8-10-26)29-17-18-36-34-30(29)20-32(39-34)28-16-11-24(19-23(28)2)21-41(3)4/h6-20,22H,5,21H2,1-4H3,(H,36,39)(H2,37,38,43)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human Aurora B by rapid dilution method				J Med Chem 53: 3973-4001 (2010) Article DOI: 10.1021/jm901870q BindingDB Entry DOI: 10.7270/Q27082CK
					More data for this Ligand-Target Pair