BDBM50316541 CHEMBL1096801::N,N'-(Propane-1,3-diyl)bis(7-hydroxy-2-imino-2H-chromene-3-carboxamide)

SMILES: Oc1ccc2cc(C(=O)NCCCNC(=O)c3cc4ccc(O)cc4oc3=N)c(=N)oc2c1

InChI Key: InChIKey=VLAVPACPOLPQDN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-1 (Rattus norvegicus)	BDBM50316541 (CHEMBL1096801 | N,N'-(Propane-1,3-diyl)bis(7-hydro...) Show SMILES Oc1ccc2cc(C(=O)NCCCNC(=O)c3cc4ccc(O)cc4oc3=N)c(=N)oc2c1 Show InChI InChI=1S/C23H20N4O6/c24-20-16(8-12-2-4-14(28)10-18(12)32-20)22(30)26-6-1-7-27-23(31)17-9-13-3-5-15(29)11-19(13)33-21(17)25/h2-5,8-11,24-25,28-29H,1,6-7H2,(H,26,30)(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...				J Med Chem 53: 4094-102 (2010) Article DOI: 10.1021/jm100119c BindingDB Entry DOI: 10.7270/Q2PZ5903
					More data for this Ligand-Target Pair
Dynamin-2 (Homo sapiens (Human))	BDBM50316541 (CHEMBL1096801 | N,N'-(Propane-1,3-diyl)bis(7-hydro...) Show SMILES Oc1ccc2cc(C(=O)NCCCNC(=O)c3cc4ccc(O)cc4oc3=N)c(=N)oc2c1 Show InChI InChI=1S/C23H20N4O6/c24-20-16(8-12-2-4-14(28)10-18(12)32-20)22(30)26-6-1-7-27-23(31)17-9-13-3-5-15(29)11-19(13)33-21(17)25/h2-5,8-11,24-25,28-29H,1,6-7H2,(H,26,30)(H,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assay				J Med Chem 53: 4094-102 (2010) Article DOI: 10.1021/jm100119c BindingDB Entry DOI: 10.7270/Q2PZ5903
					More data for this Ligand-Target Pair