BDBM50316607 2-amino-L-histidine::CHEMBL1099167::L-2-aminohistidine

SMILES: N[C@@H](Cc1cnc(N)[nH]1)C(O)=O

InChI Key: InChIKey=UYEGXSNFZXWSDV-BYPYZUCNSA-N

Data: 1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM50316607 (2-amino-L-histidine | CHEMBL1099167 | L-2-aminohis...) Show SMILES N[C@@H](Cc1cnc(N)[nH]1)C(O)=O |r| Show InChI InChI=1S/C6H10N4O2/c7-4(5(11)12)1-3-2-9-6(8)10-3/h2,4H,1,7H2,(H,11,12)(H3,8,9,10)/t4-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50316607 (2-amino-L-histidine | CHEMBL1099167 | L-2-aminohis...) Show SMILES N[C@@H](Cc1cnc(N)[nH]1)C(O)=O |r| Show InChI InChI=1S/C6H10N4O2/c7-4(5(11)12)1-3-2-9-6(8)10-3/h2,4H,1,7H2,(H,11,12)(H3,8,9,10)/t4-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
					More data for this Ligand-Target Pair
Nitric-oxide synthase, brain (Rattus norvegicus (rat))	BDBM50316607 (2-amino-L-histidine | CHEMBL1099167 | L-2-aminohis...) Show SMILES N[C@@H](Cc1cnc(N)[nH]1)C(O)=O |r| Show InChI InChI=1S/C6H10N4O2/c7-4(5(11)12)1-3-2-9-6(8)10-3/h2,4H,1,7H2,(H,11,12)(H3,8,9,10)/t4-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition rat recombinant nNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
					More data for this Ligand-Target Pair