BDBM50316734 (Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-(4-methoxy-phenyl)-thiazolidin-4-one::CHEMBL1096478

SMILES: COc1ccc(cc1)N1\C(S\C(=C/c2ccc(O)c(Cl)c2)C1=O)=N\C(C)C

InChI Key: InChIKey=MPHWXIFBAYAUSK-CXDOZEDNSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50316734 ((Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isoprop...) Show SMILES COc1ccc(cc1)N1\C(S\C(=C/c2ccc(O)c(Cl)c2)C1=O)=N\C(C)C Show InChI InChI=1S/C20H19ClN2O3S/c1-12(2)22-20-23(14-5-7-15(26-3)8-6-14)19(25)18(27-20)11-13-4-9-17(24)16(21)10-13/h4-12,24H,1-3H3/b18-11-,22-20-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	251	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Agonist activity at human recombinant S1P1 receptor expressed in CHO cells by GTPgammaS binding assay				J Med Chem 53: 4198-211 (2010) Article DOI: 10.1021/jm100181s BindingDB Entry DOI: 10.7270/Q2513ZBQ
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50316734 ((Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isoprop...) Show SMILES COc1ccc(cc1)N1\C(S\C(=C/c2ccc(O)c(Cl)c2)C1=O)=N\C(C)C Show InChI InChI=1S/C20H19ClN2O3S/c1-12(2)22-20-23(14-5-7-15(26-3)8-6-14)19(25)18(27-20)11-13-4-9-17(24)16(21)10-13/h4-12,24H,1-3H3/b18-11-,22-20-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	127	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Agonist activity at human recombinant S1P3 receptor expressed in CHO cells by GTPgammaS binding assay				J Med Chem 53: 4198-211 (2010) Article DOI: 10.1021/jm100181s BindingDB Entry DOI: 10.7270/Q2513ZBQ
					More data for this Ligand-Target Pair