BDBM50316777 2-[5-(4-Hydroxyphenethoxy)-1H-indole-3-yl]ethanamine hydrochloride::CHEMBL1095957

SMILES: NCCc1c[nH]c2ccc(OCCc3ccc(O)cc3)cc12

InChI Key: InChIKey=FVMIAPQLQLJTFD-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50316777 (2-[5-(4-Hydroxyphenethoxy)-1H-indole-3-yl]ethanami...) Show SMILES NCCc1c[nH]c2ccc(OCCc3ccc(O)cc3)cc12 Show InChI InChI=1S/C18H20N2O2/c19-9-7-14-12-20-18-6-5-16(11-17(14)18)22-10-8-13-1-3-15(21)4-2-13/h1-6,11-12,20-21H,7-10,19H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50316777 (2-[5-(4-Hydroxyphenethoxy)-1H-indole-3-yl]ethanami...) Show SMILES NCCc1c[nH]c2ccc(OCCc3ccc(O)cc3)cc12 Show InChI InChI=1S/C18H20N2O2/c19-9-7-14-12-20-18-6-5-16(11-17(14)18)22-10-8-13-1-3-15(21)4-2-13/h1-6,11-12,20-21H,7-10,19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATP				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50316777 (2-[5-(4-Hydroxyphenethoxy)-1H-indole-3-yl]ethanami...) Show SMILES NCCc1c[nH]c2ccc(OCCc3ccc(O)cc3)cc12 Show InChI InChI=1S/C18H20N2O2/c19-9-7-14-12-20-18-6-5-16(11-17(14)18)22-10-8-13-1-3-15(21)4-2-13/h1-6,11-12,20-21H,7-10,19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATP				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50316777 (2-[5-(4-Hydroxyphenethoxy)-1H-indole-3-yl]ethanami...) Show SMILES NCCc1c[nH]c2ccc(OCCc3ccc(O)cc3)cc12 Show InChI InChI=1S/C18H20N2O2/c19-9-7-14-12-20-18-6-5-16(11-17(14)18)22-10-8-13-1-3-15(21)4-2-13/h1-6,11-12,20-21H,7-10,19H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Inhibition of EGFR after 30 mins by chemiluminescence ELISA				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair