null

SMILES: COc1ccc(CCOc2ccc3n(CCCCCc4ccc(SC)cc4)cc(CCN)c3c2)cc1

InChI Key: InChIKey=GWILIXWGRREEOE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316779   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50316779 (2-{5-(4-Methoxyphenethoxy)-1-{5-[4-(methylthio)-ph...) Show SMILES COc1ccc(CCOc2ccc3n(CCCCCc4ccc(SC)cc4)cc(CCN)c3c2)cc1 Show InChI InChI=1S/C31H38N2O2S/c1-34-27-11-7-25(8-12-27)18-21-35-28-13-16-31-30(22-28)26(17-19-32)23-33(31)20-5-3-4-6-24-9-14-29(36-2)15-10-24/h7-16,22-23H,3-6,17-21,32H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50316779 (2-{5-(4-Methoxyphenethoxy)-1-{5-[4-(methylthio)-ph...) Show SMILES COc1ccc(CCOc2ccc3n(CCCCCc4ccc(SC)cc4)cc(CCN)c3c2)cc1 Show InChI InChI=1S/C31H38N2O2S/c1-34-27-11-7-25(8-12-27)18-21-35-28-13-16-31-30(22-28)26(17-19-32)23-33(31)20-5-3-4-6-24-9-14-29(36-2)15-10-24/h7-16,22-23H,3-6,17-21,32H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATP				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50316779 (2-{5-(4-Methoxyphenethoxy)-1-{5-[4-(methylthio)-ph...) Show SMILES COc1ccc(CCOc2ccc3n(CCCCCc4ccc(SC)cc4)cc(CCN)c3c2)cc1 Show InChI InChI=1S/C31H38N2O2S/c1-34-27-11-7-25(8-12-27)18-21-35-28-13-16-31-30(22-28)26(17-19-32)23-33(31)20-5-3-4-6-24-9-14-29(36-2)15-10-24/h7-16,22-23H,3-6,17-21,32H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.980	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATP				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50316779 (2-{5-(4-Methoxyphenethoxy)-1-{5-[4-(methylthio)-ph...) Show SMILES COc1ccc(CCOc2ccc3n(CCCCCc4ccc(SC)cc4)cc(CCN)c3c2)cc1 Show InChI InChI=1S/C31H38N2O2S/c1-34-27-11-7-25(8-12-27)18-21-35-28-13-16-31-30(22-28)26(17-19-32)23-33(31)20-5-3-4-6-24-9-14-29(36-2)15-10-24/h7-16,22-23H,3-6,17-21,32H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Inhibition of EGFR after 30 mins by chemiluminescence ELISA				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair