null

SMILES: COc1ccc(CCCCCn2c3CCC(N)Cc3c3cc(OCCc4ccc(O)cc4)ccc23)cc1

InChI Key: InChIKey=IGTPBMXPVDBCHU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50316781 (4-(2-(3-Amino-9-(5-(4-methoxyphenyl)pentyl)-2,3,4,...) Show SMILES COc1ccc(CCCCCn2c3CCC(N)Cc3c3cc(OCCc4ccc(O)cc4)ccc23)cc1 Show InChI InChI=1S/C32H38N2O3/c1-36-27-13-8-23(9-14-27)5-3-2-4-19-34-31-16-10-25(33)21-29(31)30-22-28(15-17-32(30)34)37-20-18-24-6-11-26(35)12-7-24/h6-9,11-15,17,22,25,35H,2-5,10,16,18-21,33H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50316781 (4-(2-(3-Amino-9-(5-(4-methoxyphenyl)pentyl)-2,3,4,...) Show SMILES COc1ccc(CCCCCn2c3CCC(N)Cc3c3cc(OCCc4ccc(O)cc4)ccc23)cc1 Show InChI InChI=1S/C32H38N2O3/c1-36-27-13-8-23(9-14-27)5-3-2-4-19-34-31-16-10-25(33)21-29(31)30-22-28(15-17-32(30)34)37-20-18-24-6-11-26(35)12-7-24/h6-9,11-15,17,22,25,35H,2-5,10,16,18-21,33H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATP				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50316781 (4-(2-(3-Amino-9-(5-(4-methoxyphenyl)pentyl)-2,3,4,...) Show SMILES COc1ccc(CCCCCn2c3CCC(N)Cc3c3cc(OCCc4ccc(O)cc4)ccc23)cc1 Show InChI InChI=1S/C32H38N2O3/c1-36-27-13-8-23(9-14-27)5-3-2-4-19-34-31-16-10-25(33)21-29(31)30-22-28(15-17-32(30)34)37-20-18-24-6-11-26(35)12-7-24/h6-9,11-15,17,22,25,35H,2-5,10,16,18-21,33H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATP				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50316781 (4-(2-(3-Amino-9-(5-(4-methoxyphenyl)pentyl)-2,3,4,...) Show SMILES COc1ccc(CCCCCn2c3CCC(N)Cc3c3cc(OCCc4ccc(O)cc4)ccc23)cc1 Show InChI InChI=1S/C32H38N2O3/c1-36-27-13-8-23(9-14-27)5-3-2-4-19-34-31-16-10-25(33)21-29(31)30-22-28(15-17-32(30)34)37-20-18-24-6-11-26(35)12-7-24/h6-9,11-15,17,22,25,35H,2-5,10,16,18-21,33H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Inhibition of EGFR after 30 mins by chemiluminescence ELISA				Bioorg Med Chem 18: 3387-402 (2010) Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT
					More data for this Ligand-Target Pair