BDBM50316853 4'-(Benzensulfonamide)-4-hydroxychalcone::CHEMBL1087322

SMILES: Oc1ccc(\C=C\C(=O)c2ccc(NS(=O)(=O)c3ccccc3)cc2)cc1

InChI Key: InChIKey=CJSVUASMASROSS-OVCLIPMQSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50316853 (4'-(Benzensulfonamide)-4-hydroxychalcone | CHEMBL1...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(NS(=O)(=O)c3ccccc3)cc2)cc1 Show InChI InChI=1S/C21H17NO4S/c23-19-13-6-16(7-14-19)8-15-21(24)17-9-11-18(12-10-17)22-27(25,26)20-4-2-1-3-5-20/h1-15,22-23H/b15-8+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Functional Crop Curated by ChEMBL					Assay Description Competitive inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burk plot analysis				Eur J Med Chem 45: 2010-7 (2010) Article DOI: 10.1016/j.ejmech.2010.01.049 BindingDB Entry DOI: 10.7270/Q2H70FZM
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50316853 (4'-(Benzensulfonamide)-4-hydroxychalcone | CHEMBL1...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(NS(=O)(=O)c3ccccc3)cc2)cc1 Show InChI InChI=1S/C21H17NO4S/c23-19-13-6-16(7-14-19)8-15-21(24)17-9-11-18(12-10-17)22-27(25,26)20-4-2-1-3-5-20/h1-15,22-23H/b15-8+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Functional Crop Curated by ChEMBL					Assay Description Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by spectrophotometric analysis				Eur J Med Chem 45: 2010-7 (2010) Article DOI: 10.1016/j.ejmech.2010.01.049 BindingDB Entry DOI: 10.7270/Q2H70FZM
					More data for this Ligand-Target Pair