BDBM50316854 4'-(4-Hydroxylbenzensulfonamide)-4-hydroxychalcone::CHEMBL1087323
SMILES: Oc1ccc(\C=C\C(=O)c2ccc(NS(=O)(=O)c3ccc(O)cc3)cc2)cc1
InChI Key: InChIKey=AKFSIRURRSIJQR-LZWSPWQCSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50316854 (4'-(4-Hydroxylbenzensulfonamide)-4-hydroxychalcone...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Functional Crop Curated by ChEMBL | Assay Description Competitive inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burk plot analysis | Eur J Med Chem 45: 2010-7 (2010) Article DOI: 10.1016/j.ejmech.2010.01.049 BindingDB Entry DOI: 10.7270/Q2H70FZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50316854 (4'-(4-Hydroxylbenzensulfonamide)-4-hydroxychalcone...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Functional Crop Curated by ChEMBL | Assay Description Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by spectrophotometric analysis | Eur J Med Chem 45: 2010-7 (2010) Article DOI: 10.1016/j.ejmech.2010.01.049 BindingDB Entry DOI: 10.7270/Q2H70FZM | |||||||||||
More data for this Ligand-Target Pair |