BDBM50316930 2-(1-cyclohexylpiperidin-3-yl)-1-(4-fluorobenzyl)-1H-benzo[d]imidazole::CHEMBL1094525

SMILES: Fc1ccc(Cn2c(nc3ccccc23)C2CCCN(C2)C2CCCCC2)cc1

InChI Key: InChIKey=HJXPDUZXVIVZJB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50316930 (2-(1-cyclohexylpiperidin-3-yl)-1-(4-fluorobenzyl)-...) Show SMILES Fc1ccc(Cn2c(nc3ccccc23)C2CCCN(C2)C2CCCCC2)cc1 Show InChI InChI=1S/C25H30FN3/c26-21-14-12-19(13-15-21)17-29-24-11-5-4-10-23(24)27-25(29)20-7-6-16-28(18-20)22-8-2-1-3-9-22/h4-5,10-15,20,22H,1-3,6-9,16-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	926	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]dofetolide from human ERG channel expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem Lett 20: 2916-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.027 BindingDB Entry DOI: 10.7270/Q20865G0
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50316930 (2-(1-cyclohexylpiperidin-3-yl)-1-(4-fluorobenzyl)-...) Show SMILES Fc1ccc(Cn2c(nc3ccccc23)C2CCCN(C2)C2CCCCC2)cc1 Show InChI InChI=1S/C25H30FN3/c26-21-14-12-19(13-15-21)17-29-24-11-5-4-10-23(24)27-25(29)20-7-6-16-28(18-20)22-8-2-1-3-9-22/h4-5,10-15,20,22H,1-3,6-9,16-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Bioorg Med Chem Lett 20: 2916-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.027 BindingDB Entry DOI: 10.7270/Q20865G0
					More data for this Ligand-Target Pair