BDBM50316964 CHEMBL1086961::N'-cyano-N-(3-(4-(pyridin-2-yl)piperazin-1-yl)propyl)isonicotinamidine

SMILES: N#CNC(=NCCCN1CCN(CC1)c1ccccn1)c1ccncc1

InChI Key: InChIKey=JPCJGSJYXPPMAF-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50316964 (CHEMBL1086961 | N'-cyano-N-(3-(4-(pyridin-2-yl)pip...) Show SMILES N#CNC(=NCCCN1CCN(CC1)c1ccccn1)c1ccncc1 |w:4.4| Show InChI InChI=1S/C19H23N7/c20-16-24-19(17-5-9-21-10-6-17)23-8-3-11-25-12-14-26(15-13-25)18-4-1-2-7-22-18/h1-2,4-7,9-10H,3,8,11-15H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.0380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat brain cortex after 30 mins liquid scintillation spectrometer				Bioorg Med Chem Lett 20: 2978-82 (2010) Article DOI: 10.1016/j.bmcl.2010.02.106 BindingDB Entry DOI: 10.7270/Q2QR4X80
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50316964 (CHEMBL1086961 | N'-cyano-N-(3-(4-(pyridin-2-yl)pip...) Show SMILES N#CNC(=NCCCN1CCN(CC1)c1ccccn1)c1ccncc1 |w:4.4| Show InChI InChI=1S/C19H23N7/c20-16-24-19(17-5-9-21-10-6-17)23-8-3-11-25-12-14-26(15-13-25)18-4-1-2-7-22-18/h1-2,4-7,9-10H,3,8,11-15H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum after 15 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2978-82 (2010) Article DOI: 10.1016/j.bmcl.2010.02.106 BindingDB Entry DOI: 10.7270/Q2QR4X80
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50316964 (CHEMBL1086961 | N'-cyano-N-(3-(4-(pyridin-2-yl)pip...) Show SMILES N#CNC(=NCCCN1CCN(CC1)c1ccccn1)c1ccncc1 |w:4.4| Show InChI InChI=1S/C19H23N7/c20-16-24-19(17-5-9-21-10-6-17)23-8-3-11-25-12-14-26(15-13-25)18-4-1-2-7-22-18/h1-2,4-7,9-10H,3,8,11-15H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat striatum after 15 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2978-82 (2010) Article DOI: 10.1016/j.bmcl.2010.02.106 BindingDB Entry DOI: 10.7270/Q2QR4X80
					More data for this Ligand-Target Pair