BDBM50317139 5-(2-(diethylamino)ethylamino)-7-hydroxy-10-methoxy-6H-imidazo[4,5,1-de]acridin-6-one::5-(2-Diethylamino-ethylamino)-7-hydroxy-10-methoxy-2,10b-diaza-aceanthrylen-6-one::CHEMBL8219::NSC-660840
SMILES: CCN(CC)CCNc1ccc2ncn3c2c1c(=O)c1c(O)ccc(OC)c31
InChI Key: InChIKey=AWMRRELRWBHCHQ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Ribosyldihydronicotinamide dehydrogenase [quinone] (Homo sapiens (Human)) | BDBM50317139 (5-(2-(diethylamino)ethylamino)-7-hydroxy-10-methox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center Curated by ChEMBL | Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry | Bioorg Med Chem Lett 20: 2832-6 (2010) Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K | |||||||||||
More data for this Ligand-Target Pair |