BDBM50317183 2-[11-(beta-Carboline-2-ium-2-yl)undecyl]-beta-carboline-2-ium dibromide::CHEMBL1087968

SMILES: C(CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21)CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21

InChI Key: InChIKey=UYHDNAKZDXNCHU-UHFFFAOYSA-P

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50317183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50317183 (2-[11-(beta-Carboline-2-ium-2-yl)undecyl]-beta-car...) Show SMILES C(CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21)CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21 Show InChI InChI=1S/C33H36N4/c1(2-4-6-12-20-36-22-18-28-26-14-8-10-16-30(26)34-32(28)24-36)3-5-7-13-21-37-23-19-29-27-15-9-11-17-31(27)35-33(29)25-37/h8-11,14-19,22-25H,1-7,12-13,20-21H2/p+2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universitat Jena Curated by ChEMBL					Assay Description Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assesse...				J Med Chem 53: 3611-7 (2010) Article DOI: 10.1021/jm1000024 BindingDB Entry DOI: 10.7270/Q2SJ1KS0
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50317183 (2-[11-(beta-Carboline-2-ium-2-yl)undecyl]-beta-car...) Show SMILES C(CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21)CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21 Show InChI InChI=1S/C33H36N4/c1(2-4-6-12-20-36-22-18-28-26-14-8-10-16-30(26)34-32(28)24-36)3-5-7-13-21-37-23-19-29-27-15-9-11-17-31(27)35-33(29)25-37/h8-11,14-19,22-25H,1-7,12-13,20-21H2/p+2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universitat Jena Curated by ChEMBL					Assay Description Inhibition of electric eel AChE by modified Ellman's method				J Med Chem 53: 3611-7 (2010) Article DOI: 10.1021/jm1000024 BindingDB Entry DOI: 10.7270/Q2SJ1KS0
					More data for this Ligand-Target Pair
Butyrylcholinesterase (BuChE) (Equus caballus (Horse))	BDBM50317183 (2-[11-(beta-Carboline-2-ium-2-yl)undecyl]-beta-car...) Show SMILES C(CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21)CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21 Show InChI InChI=1S/C33H36N4/c1(2-4-6-12-20-36-22-18-28-26-14-8-10-16-30(26)34-32(28)24-36)3-5-7-13-21-37-23-19-29-27-15-9-11-17-31(27)35-33(29)25-37/h8-11,14-19,22-25H,1-7,12-13,20-21H2/p+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universitat Jena Curated by ChEMBL					Assay Description Inhibition of equine serum BChE by modified Ellman's method				J Med Chem 53: 3611-7 (2010) Article DOI: 10.1021/jm1000024 BindingDB Entry DOI: 10.7270/Q2SJ1KS0
					More data for this Ligand-Target Pair
NR1/NR2A (Homo sapiens (Human))	BDBM50317183 (2-[11-(beta-Carboline-2-ium-2-yl)undecyl]-beta-car...) Show SMILES C(CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21)CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21 Show InChI InChI=1S/C33H36N4/c1(2-4-6-12-20-36-22-18-28-26-14-8-10-16-30(26)34-32(28)24-36)3-5-7-13-21-37-23-19-29-27-15-9-11-17-31(27)35-33(29)25-37/h8-11,14-19,22-25H,1-7,12-13,20-21H2/p+2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universitat Jena Curated by ChEMBL					Assay Description Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...				J Med Chem 53: 3611-7 (2010) Article DOI: 10.1021/jm1000024 BindingDB Entry DOI: 10.7270/Q2SJ1KS0
					More data for this Ligand-Target Pair