BDBM50317206 (3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone::CHEMBL1088379

SMILES: O=C(N1CCCCC1)C12CC3CC(C1)CC(C3)(C2)c1ccccc1

InChI Key: InChIKey=GRJCFVZPAQAKFW-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50317206 ((3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone...) Show SMILES O=C(N1CCCCC1)C12CC3CC(C1)CC(C3)(C2)c1ccccc1 |TLB:13:8:16:14.12.11,1:8:16:14.12.11,1:8:16.15.14:11,THB:18:15:11:9.8.13,17:15:11:9.8.13,17:8:16.15.14:11,13:12:16:9.17.8| Show InChI InChI=1S/C22H29NO/c24-20(23-9-5-2-6-10-23)22-14-17-11-18(15-22)13-21(12-17,16-22)19-7-3-1-4-8-19/h1,3-4,7-8,17-18H,2,5-6,9-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of human 11-beta-HSD1				Bioorg Med Chem Lett 20: 2897-902 (2010) Article DOI: 10.1016/j.bmcl.2010.03.032 BindingDB Entry DOI: 10.7270/Q2NV9JDJ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 2 (Homo sapiens (Human))	BDBM50317206 ((3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone...) Show SMILES O=C(N1CCCCC1)C12CC3CC(C1)CC(C3)(C2)c1ccccc1 |TLB:13:8:16:14.12.11,1:8:16:14.12.11,1:8:16.15.14:11,THB:18:15:11:9.8.13,17:15:11:9.8.13,17:8:16.15.14:11,13:12:16:9.17.8| Show InChI InChI=1S/C22H29NO/c24-20(23-9-5-2-6-10-23)22-14-17-11-18(15-22)13-21(12-17,16-22)19-7-3-1-4-8-19/h1,3-4,7-8,17-18H,2,5-6,9-16H2	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of 11-beta-HSD2				Bioorg Med Chem Lett 20: 2897-902 (2010) Article DOI: 10.1016/j.bmcl.2010.03.032 BindingDB Entry DOI: 10.7270/Q2NV9JDJ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50317206 ((3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone...) Show SMILES O=C(N1CCCCC1)C12CC3CC(C1)CC(C3)(C2)c1ccccc1 |TLB:13:8:16:14.12.11,1:8:16:14.12.11,1:8:16.15.14:11,THB:18:15:11:9.8.13,17:15:11:9.8.13,17:8:16.15.14:11,13:12:16:9.17.8| Show InChI InChI=1S/C22H29NO/c24-20(23-9-5-2-6-10-23)22-14-17-11-18(15-22)13-21(12-17,16-22)19-7-3-1-4-8-19/h1,3-4,7-8,17-18H,2,5-6,9-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 2897-902 (2010) Article DOI: 10.1016/j.bmcl.2010.03.032 BindingDB Entry DOI: 10.7270/Q2NV9JDJ
					More data for this Ligand-Target Pair