BDBM50317356 3-(3-stearoyl-1H-pyrazole-5-carboxamido)thiophene-2-carboxylic acid::CHEMBL1095726

SMILES: CCCCCCCCCCCCCCCCCC(=O)c1cc([nH]n1)C(=O)Nc1ccsc1C(O)=O

InChI Key: InChIKey=IPYSLWNCHIOLRH-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50317356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50317356 (3-(3-stearoyl-1H-pyrazole-5-carboxamido)thiophene-...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1cc([nH]n1)C(=O)Nc1ccsc1C(O)=O Show InChI InChI=1S/C27H41N3O4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(31)22-20-23(30-29-22)26(32)28-21-18-19-35-25(21)27(33)34/h18-20H,2-17H2,1H3,(H,28,32)(H,29,30)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of PTP1B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM50317356 (3-(3-stearoyl-1H-pyrazole-5-carboxamido)thiophene-...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1cc([nH]n1)C(=O)Nc1ccsc1C(O)=O Show InChI InChI=1S/C27H41N3O4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(31)22-20-23(30-29-22)26(32)28-21-18-19-35-25(21)27(33)34/h18-20H,2-17H2,1H3,(H,28,32)(H,29,30)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50317356 (3-(3-stearoyl-1H-pyrazole-5-carboxamido)thiophene-...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1cc([nH]n1)C(=O)Nc1ccsc1C(O)=O Show InChI InChI=1S/C27H41N3O4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(31)22-20-23(30-29-22)26(32)28-21-18-19-35-25(21)27(33)34/h18-20H,2-17H2,1H3,(H,28,32)(H,29,30)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of SHP2				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1C (Homo sapiens (Human))	BDBM50317356 (3-(3-stearoyl-1H-pyrazole-5-carboxamido)thiophene-...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1cc([nH]n1)C(=O)Nc1ccsc1C(O)=O Show InChI InChI=1S/C27H41N3O4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(31)22-20-23(30-29-22)26(32)28-21-18-19-35-25(21)27(33)34/h18-20H,2-17H2,1H3,(H,28,32)(H,29,30)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of SHP1				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50317356 (3-(3-stearoyl-1H-pyrazole-5-carboxamido)thiophene-...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1cc([nH]n1)C(=O)Nc1ccsc1C(O)=O Show InChI InChI=1S/C27H41N3O4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(31)22-20-23(30-29-22)26(32)28-21-18-19-35-25(21)27(33)34/h18-20H,2-17H2,1H3,(H,28,32)(H,29,30)(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of TCPTP				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
					More data for this Ligand-Target Pair