BDBM50317389 5-(Aminosulfonyl)-N-benzyl-2-(benzylthio)benzamide::CHEMBL1098206

SMILES: NS(=O)(=O)c1ccc(SCc2ccccc2)c(c1)C(=O)NCc1ccccc1

InChI Key: InChIKey=UWXYGZQIRPAISJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50317389 (5-(Aminosulfonyl)-N-benzyl-2-(benzylthio)benzamide...) Show SMILES NS(=O)(=O)c1ccc(SCc2ccccc2)c(c1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C21H20N2O3S2/c22-28(25,26)18-11-12-20(27-15-17-9-5-2-6-10-17)19(13-18)21(24)23-14-16-7-3-1-4-8-16/h1-13H,14-15H2,(H,23,24)(H2,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of carbonic anhydrase 4				Bioorg Med Chem 18: 3307-19 (2010) Article DOI: 10.1016/j.bmc.2010.03.014 BindingDB Entry DOI: 10.7270/Q2SQ91B9
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50317389 (5-(Aminosulfonyl)-N-benzyl-2-(benzylthio)benzamide...) Show SMILES NS(=O)(=O)c1ccc(SCc2ccccc2)c(c1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C21H20N2O3S2/c22-28(25,26)18-11-12-20(27-15-17-9-5-2-6-10-17)19(13-18)21(24)23-14-16-7-3-1-4-8-16/h1-13H,14-15H2,(H,23,24)(H2,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of carbonic anhydrase 2				Bioorg Med Chem 18: 3307-19 (2010) Article DOI: 10.1016/j.bmc.2010.03.014 BindingDB Entry DOI: 10.7270/Q2SQ91B9
					More data for this Ligand-Target Pair