BDBM50317396 5-(Aminosulfonyl)-N-benzyl-2-(phenylsulfonyl)benzamide::CHEMBL1098526

SMILES: NS(=O)(=O)c1ccc(c(c1)C(=O)NCc1ccccc1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=ZULOSPOKQJSTNL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50317396 (5-(Aminosulfonyl)-N-benzyl-2-(phenylsulfonyl)benza...) Show SMILES NS(=O)(=O)c1ccc(c(c1)C(=O)NCc1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H18N2O5S2/c21-29(26,27)17-11-12-19(28(24,25)16-9-5-2-6-10-16)18(13-17)20(23)22-14-15-7-3-1-4-8-15/h1-13H,14H2,(H,22,23)(H2,21,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of carbonic anhydrase 4				Bioorg Med Chem 18: 3307-19 (2010) Article DOI: 10.1016/j.bmc.2010.03.014 BindingDB Entry DOI: 10.7270/Q2SQ91B9
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50317396 (5-(Aminosulfonyl)-N-benzyl-2-(phenylsulfonyl)benza...) Show SMILES NS(=O)(=O)c1ccc(c(c1)C(=O)NCc1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H18N2O5S2/c21-29(26,27)17-11-12-19(28(24,25)16-9-5-2-6-10-16)18(13-17)20(23)22-14-15-7-3-1-4-8-15/h1-13H,14H2,(H,22,23)(H2,21,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of carbonic anhydrase 2				Bioorg Med Chem 18: 3307-19 (2010) Article DOI: 10.1016/j.bmc.2010.03.014 BindingDB Entry DOI: 10.7270/Q2SQ91B9
					More data for this Ligand-Target Pair