BDBM50317731 4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1095714

SMILES: CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F

InChI Key: InChIKey=KIITVWQUUAGGON-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50317731 (4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluorom...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F Show InChI InChI=1S/C23H16F3NO2S/c1-30(28,29)18-8-3-6-16(14-18)15-5-2-7-17(13-15)19-11-12-27-22-20(19)9-4-10-21(22)23(24,25)26/h2-14H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from LXRbeta ligand binding domain				Bioorg Med Chem Lett 20: 2903-7 (2010) Article DOI: 10.1016/j.bmcl.2010.03.031 BindingDB Entry DOI: 10.7270/Q2TD9XJZ
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50317731 (4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluorom...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F Show InChI InChI=1S/C23H16F3NO2S/c1-30(28,29)18-8-3-6-16(14-18)15-5-2-7-17(13-15)19-11-12-27-22-20(19)9-4-10-21(22)23(24,25)26/h2-14H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from LXRalpha ligand binding domain				Bioorg Med Chem Lett 20: 2903-7 (2010) Article DOI: 10.1016/j.bmcl.2010.03.031 BindingDB Entry DOI: 10.7270/Q2TD9XJZ
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50317731 (4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluorom...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F Show InChI InChI=1S/C23H16F3NO2S/c1-30(28,29)18-8-3-6-16(14-18)15-5-2-7-17(13-15)19-11-12-27-22-20(19)9-4-10-21(22)23(24,25)26/h2-14H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	525	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human recombinant LXRbeta ligand binding domain in HuH7 cells by Gal4 transactivation assay				Bioorg Med Chem Lett 20: 2903-7 (2010) Article DOI: 10.1016/j.bmcl.2010.03.031 BindingDB Entry DOI: 10.7270/Q2TD9XJZ
					More data for this Ligand-Target Pair