BDBM50317820 3-(3-fluorobenzyl)5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate::CHEMBL1097157

SMILES: COC(=O)C1C(C(C(=O)OCc2cccc(F)c2)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O

InChI Key: InChIKey=KMNDOCKUJXUOGX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50317820 (3-(3-fluorobenzyl)5-methyl 2,6-dimethyl-4-(3-nitro...) Show SMILES COC(=O)C1C(C(C(=O)OCc2cccc(F)c2)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O |c:21,t:18| Show InChI InChI=1S/C23H21FN2O6/c1-13-19(22(27)31-3)21(16-7-5-9-18(11-16)26(29)30)20(14(2)25-13)23(28)32-12-15-6-4-8-17(24)10-15/h4-11,19,21H,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...				Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50317820 (3-(3-fluorobenzyl)5-methyl 2,6-dimethyl-4-(3-nitro...) Show SMILES COC(=O)C1C(C(C(=O)OCc2cccc(F)c2)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O |c:21,t:18| Show InChI InChI=1S/C23H21FN2O6/c1-13-19(22(27)31-3)21(16-7-5-9-18(11-16)26(29)30)20(14(2)25-13)23(28)32-12-15-6-4-8-17(24)10-15/h4-11,19,21H,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay				Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90
					More data for this Ligand-Target Pair