BDBM50317854 5-((6-Methylpyridin-2-yl)ethynyl)nicotinonitrile::CHEMBL1098656

SMILES: Cc1cccc(n1)C#Cc1cncc(c1)C#N

InChI Key: InChIKey=ZWOWJRDKGWIZDL-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317854   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50317854 (5-((6-Methylpyridin-2-yl)ethynyl)nicotinonitrile |...) Show SMILES Cc1cccc(n1)C#Cc1cncc(c1)C#N Show InChI InChI=1S/C14H9N3/c1-11-3-2-4-14(17-11)6-5-12-7-13(8-15)10-16-9-12/h2-4,7,9-10H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3HMPEP from rat cloned mGluR5 expressed in HEK293T cells by by scintillation counting				Bioorg Med Chem 18: 3026-35 (2010) Article DOI: 10.1016/j.bmc.2010.03.053 BindingDB Entry DOI: 10.7270/Q29C6XK8
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50317854 (5-((6-Methylpyridin-2-yl)ethynyl)nicotinonitrile |...) Show SMILES Cc1cccc(n1)C#Cc1cncc(c1)C#N Show InChI InChI=1S/C14H9N3/c1-11-3-2-4-14(17-11)6-5-12-7-13(8-15)10-16-9-12/h2-4,7,9-10H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincubated for 140 secs befor...				Bioorg Med Chem 18: 3026-35 (2010) Article DOI: 10.1016/j.bmc.2010.03.053 BindingDB Entry DOI: 10.7270/Q29C6XK8
					More data for this Ligand-Target Pair