BDBM50317908 3-{2-({[(1R)-1-(3,5-Dimethylphenyl)-3-methylbutyl]-amino}carbonyl)-4-[(2-methylphenoxy)methyl]phenyl}-propanoic acid::CHEMBL1094157
SMILES: CC(C)C[C@@H](NC(=O)c1cc(COc2ccccc2C)ccc1CCC(O)=O)c1cc(C)cc(C)c1
InChI Key: InChIKey=PUQCPIMXFYPCIE-MUUNZHRXSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50317908 (3-{2-({[(1R)-1-(3,5-Dimethylphenyl)-3-methylbutyl]...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem 18: 3212-23 (2010) Article DOI: 10.1016/j.bmc.2010.03.028 BindingDB Entry DOI: 10.7270/Q2SF2WB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50317908 (3-{2-({[(1R)-1-(3,5-Dimethylphenyl)-3-methylbutyl]...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem 18: 3212-23 (2010) Article DOI: 10.1016/j.bmc.2010.03.028 BindingDB Entry DOI: 10.7270/Q2SF2WB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50317908 (3-{2-({[(1R)-1-(3,5-Dimethylphenyl)-3-methylbutyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem 18: 3212-23 (2010) Article DOI: 10.1016/j.bmc.2010.03.028 BindingDB Entry DOI: 10.7270/Q2SF2WB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50317908 (3-{2-({[(1R)-1-(3,5-Dimethylphenyl)-3-methylbutyl]...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counting | Bioorg Med Chem 18: 3212-23 (2010) Article DOI: 10.1016/j.bmc.2010.03.028 BindingDB Entry DOI: 10.7270/Q2SF2WB7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50317908 (3-{2-({[(1R)-1-(3,5-Dimethylphenyl)-3-methylbutyl]...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ... | Bioorg Med Chem 18: 3212-23 (2010) Article DOI: 10.1016/j.bmc.2010.03.028 BindingDB Entry DOI: 10.7270/Q2SF2WB7 | |||||||||||
More data for this Ligand-Target Pair |