Found 3 hits for monomerid = 50317968 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50317968
((R)-N-hydroxy-3-(3-(1-(1-phenylethyl)-1H-benzo[d]i...)Show SMILES C[C@H](c1ccccc1)n1c(nc2ccccc12)-c1cccc(\C=C\C(=O)NO)c1 |r| Show InChI InChI=1S/C24H21N3O2/c1-17(19-9-3-2-4-10-19)27-22-13-6-5-12-21(22)25-24(27)20-11-7-8-18(16-20)14-15-23(28)26-29/h2-17,29H,1H3,(H,26,28)/b15-14+/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC8 |
Bioorg Med Chem Lett 20: 3138-41 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.092 BindingDB Entry DOI: 10.7270/Q2514058 |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50317968
((R)-N-hydroxy-3-(3-(1-(1-phenylethyl)-1H-benzo[d]i...)Show SMILES C[C@H](c1ccccc1)n1c(nc2ccccc12)-c1cccc(\C=C\C(=O)NO)c1 |r| Show InChI InChI=1S/C24H21N3O2/c1-17(19-9-3-2-4-10-19)27-22-13-6-5-12-21(22)25-24(27)20-11-7-8-18(16-20)14-15-23(28)26-29/h2-17,29H,1H3,(H,26,28)/b15-14+/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC6 |
Bioorg Med Chem Lett 20: 3138-41 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.092 BindingDB Entry DOI: 10.7270/Q2514058 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50317968
((R)-N-hydroxy-3-(3-(1-(1-phenylethyl)-1H-benzo[d]i...)Show SMILES C[C@H](c1ccccc1)n1c(nc2ccccc12)-c1cccc(\C=C\C(=O)NO)c1 |r| Show InChI InChI=1S/C24H21N3O2/c1-17(19-9-3-2-4-10-19)27-22-13-6-5-12-21(22)25-24(27)20-11-7-8-18(16-20)14-15-23(28)26-29/h2-17,29H,1H3,(H,26,28)/b15-14+/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC2 |
Bioorg Med Chem Lett 20: 3138-41 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.092 BindingDB Entry DOI: 10.7270/Q2514058 |
More data for this Ligand-Target Pair | |