BDBM50318487 CHEMBL497318::Cannabigerol
SMILES: [#6]-[#6]-[#6]-[#6]-[#6]-c1cc(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c1
InChI Key: InChIKey=QXACEHWTBCFNSA-SFQUDFHCSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 153 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Concordia University Wisconsin Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from recombinant human CB2 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 ... | J Nat Prod 82: 636-646 (2019) Article DOI: 10.1021/acs.jnatprod.8b00874 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 mins | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 mins | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 880 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 mins | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 897 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Concordia University Wisconsin Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from recombinant human CB1 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 ... | J Nat Prod 82: 636-646 (2019) Article DOI: 10.1021/acs.jnatprod.8b00874 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vanilloid receptor (Rattus norvegicus) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Agonist activity at rat recombinant TRPV2 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dy... | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 700 | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Agonist activity at rat recombinant TRPA1 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dy... | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential M8 protein (TRPM8) (Rattus norvegicus (Rat)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat recombinant TRPM8 receptor expressed in HEK293 cells assessed as inhibition of 0.25 uM icilin-induced stimulation of intra... | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a |
Ferrara University Curated by ChEMBL | Assay Description Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influx | J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Concordia University Wisconsin Curated by ChEMBL | Assay Description Inhibition of FAAH in rat brain membranes using [14C]-AEA as substrate measured after 30 mins by scintillation counting method | J Nat Prod 82: 636-646 (2019) Article DOI: 10.1021/acs.jnatprod.8b00874 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sn1-specific diacylglycerol lipase alpha (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Concordia University Wisconsin Curated by ChEMBL | Assay Description Inhibition of recombinant human DAGLalpha expressed in COS7 cells using [14C]-oleoyl-2-arachidonoyl-glycerol as substrate measured after 20 mins by b... | J Nat Prod 82: 636-646 (2019) Article DOI: 10.1021/acs.jnatprod.8b00874 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Concordia University Wisconsin Curated by ChEMBL | Assay Description Inhibition of recombinant human NAAA expressed in HEK293 cells using [14C]-N-palmitoylethanolamine as substrate measured after 30 mins by beta-counti... | J Nat Prod 82: 636-646 (2019) Article DOI: 10.1021/acs.jnatprod.8b00874 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 mins | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vanilloid receptor (Rattus norvegicus) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Agonist activity at rat recombinant TRPV2 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dy... | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat recombinant TRPA1 receptor expressed in HEK293 cells assessed as inhibition of 100 uM allyl isothiocyanate-induced stimula... | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.57E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6... | J Nat Prod 83: 1711-1715 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at human TRPv1 receptor expressed in HEK293 cells assessed as inhibition of 0.1 um capsaicin-induced stimulation of intracellular... | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50318487 (CHEMBL497318 | Cannabigerol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
Universita` del Piemonte Orientale Curated by ChEMBL | Assay Description Agonist activity at human TRPv1 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dye based fl... | J Nat Prod 74: 2019-22 (2011) Article DOI: 10.1021/np200500p BindingDB Entry DOI: 10.7270/Q2BR8SKG | |||||||||||
More data for this Ligand-Target Pair |