null

SMILES: Brc1cnc2nc[nH]c2c1N1CCN(CC(=O)Nc2nccs2)CC1

InChI Key: InChIKey=KHNWPAGJZMTRNT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50318571 (2-[4-(6-Bromo-3H-imidazo[4,5-b]pyridin-7-yl)-piper...) Show SMILES Brc1cnc2nc[nH]c2c1N1CCN(CC(=O)Nc2nccs2)CC1 Show InChI InChI=1S/C15H16BrN7OS/c16-10-7-18-14-12(19-9-20-14)13(10)23-4-2-22(3-5-23)8-11(24)21-15-17-1-6-25-15/h1,6-7,9H,2-5,8H2,(H,17,21,24)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	517	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human recombinant Aurora A expressed in baculovirus system				J Med Chem 53: 5213-28 (2010) Article DOI: 10.1021/jm100262j BindingDB Entry DOI: 10.7270/Q2GB251P
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50318571 (2-[4-(6-Bromo-3H-imidazo[4,5-b]pyridin-7-yl)-piper...) Show SMILES Brc1cnc2nc[nH]c2c1N1CCN(CC(=O)Nc2nccs2)CC1 Show InChI InChI=1S/C15H16BrN7OS/c16-10-7-18-14-12(19-9-20-14)13(10)23-4-2-22(3-5-23)8-11(24)21-15-17-1-6-25-15/h1,6-7,9H,2-5,8H2,(H,17,21,24)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of Aurora A				Eur J Med Chem 46: 77-94 (2010) Article DOI: 10.1016/j.ejmech.2010.10.017 BindingDB Entry DOI: 10.7270/Q25X296N
					More data for this Ligand-Target Pair