BDBM50318677 4-Chloro-2-{[2-(4-hydroxyphenyl)-1,3-dioxo-2,3-dihydro-1Hisoindole-5-carbonyl]amino}benzoic Acid::CHEMBL1084248

SMILES: OC(=O)c1ccc(Cl)cc1NC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1ccc(O)cc1

InChI Key: InChIKey=SEVZMDZOXGHKNY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-2 (Homo sapiens (Human))	BDBM50318677 (4-Chloro-2-{[2-(4-hydroxyphenyl)-1,3-dioxo-2,3-dih...) Show SMILES OC(=O)c1ccc(Cl)cc1NC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1ccc(O)cc1 Show InChI InChI=1S/C22H13ClN2O6/c23-12-2-8-16(22(30)31)18(10-12)24-19(27)11-1-7-15-17(9-11)21(29)25(20(15)28)13-3-5-14(26)6-4-13/h1-10,26H,(H,24,27)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green method				J Med Chem 53: 5267-80 (2010) Article DOI: 10.1021/jm100442u BindingDB Entry DOI: 10.7270/Q2PV6MBN
					More data for this Ligand-Target Pair