BDBM50318687 4-(Azepan-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate::CHEMBL1082838

SMILES: O=C(Oc1nsnc1N1CCCCCC1)N1CCCCC1

InChI Key: InChIKey=CPJBLWHNLPCXEJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318687   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid lipase/cholesteryl ester hydrolase (Homo sapiens (Human))	BDBM50318687 (4-(Azepan-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1...) Show SMILES O=C(Oc1nsnc1N1CCCCCC1)N1CCCCC1 Show InChI InChI=1S/C14H22N4O2S/c19-14(18-10-6-3-7-11-18)20-13-12(15-21-16-13)17-8-4-1-2-5-9-17/h1-11H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of human LAL after 30 mins by fluorescence assay				J Med Chem 53: 5281-9 (2010) Article DOI: 10.1021/jm100499s BindingDB Entry DOI: 10.7270/Q2FB53XB
					More data for this Ligand-Target Pair