BDBM50319011 4-(5-chloro-3-methylbenzo[b]thiophen-2-yl)pyridine::CHEMBL1083142

SMILES: Cc1c(sc2ccc(Cl)cc12)-c1ccncc1

InChI Key: InChIKey=WRMSCOBQKNUWGB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50319011 (4-(5-chloro-3-methylbenzo[b]thiophen-2-yl)pyridine...) Show SMILES Cc1c(sc2ccc(Cl)cc12)-c1ccncc1 Show InChI InChI=1S/C14H10ClNS/c1-9-12-8-11(15)2-3-13(12)17-14(9)10-4-6-16-7-5-10/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kalypsys, Inc. Curated by ChEMBL					Assay Description Inhibition of ROCK1 assessed as ATP cunsumption				Bioorg Med Chem Lett 20: 3361-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.020 BindingDB Entry DOI: 10.7270/Q289161H
					More data for this Ligand-Target Pair