BDBM50319219 6-[3-(4-pyrimidin-5-yl-benzoyl)-ureido]-hexanoic acid hydroxyamide::CHEMBL1082955

SMILES: ONC(=O)CCCCCNC(=O)NC(=O)c1ccc(cc1)-c1cncnc1

InChI Key: InChIKey=UTTBZVIOMLTFET-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50319219 (6-[3-(4-pyrimidin-5-yl-benzoyl)-ureido]-hexanoic a...) Show SMILES ONC(=O)CCCCCNC(=O)NC(=O)c1ccc(cc1)-c1cncnc1 Show InChI InChI=1S/C18H21N5O4/c24-16(23-27)4-2-1-3-9-21-18(26)22-17(25)14-7-5-13(6-8-14)15-10-19-12-20-11-15/h5-8,10-12,27H,1-4,9H2,(H,23,24)(H2,21,22,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
S *BIO Pte Ltd Curated by ChEMBL					Assay Description Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylation				Bioorg Med Chem Lett 20: 3314-21 (2010) Article DOI: 10.1016/j.bmcl.2010.04.041 BindingDB Entry DOI: 10.7270/Q2GT5NCX
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50319219 (6-[3-(4-pyrimidin-5-yl-benzoyl)-ureido]-hexanoic a...) Show SMILES ONC(=O)CCCCCNC(=O)NC(=O)c1ccc(cc1)-c1cncnc1 Show InChI InChI=1S/C18H21N5O4/c24-16(23-27)4-2-1-3-9-21-18(26)22-17(25)14-7-5-13(6-8-14)15-10-19-12-20-11-15/h5-8,10-12,27H,1-4,9H2,(H,23,24)(H2,21,22,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
S *BIO Pte Ltd Curated by ChEMBL					Assay Description Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylation				Bioorg Med Chem Lett 20: 3314-21 (2010) Article DOI: 10.1016/j.bmcl.2010.04.041 BindingDB Entry DOI: 10.7270/Q2GT5NCX
					More data for this Ligand-Target Pair