BDBM50319281 1-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)propyl)piperidin-3-amine::CHEMBL1083085

SMILES: Cc1cc(OCCCN2CCCC(N)C2)ccc1-c1nc2ccc(F)c(C)c2[nH]1

InChI Key: InChIKey=NGYCNCUOXVCKSV-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50319281 (1-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-y...) Show SMILES Cc1cc(OCCCN2CCCC(N)C2)ccc1-c1nc2ccc(F)c(C)c2[nH]1 Show InChI InChI=1S/C23H29FN4O/c1-15-13-18(29-12-4-11-28-10-3-5-17(25)14-28)6-7-19(15)23-26-21-9-8-20(24)16(2)22(21)27-23/h6-9,13,17H,3-5,10-12,14,25H2,1-2H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50319281 (1-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-y...) Show SMILES Cc1cc(OCCCN2CCCC(N)C2)ccc1-c1nc2ccc(F)c(C)c2[nH]1 Show InChI InChI=1S/C23H29FN4O/c1-15-13-18(29-12-4-11-28-10-3-5-17(25)14-28)6-7-19(15)23-26-21-9-8-20(24)16(2)22(21)27-23/h6-9,13,17H,3-5,10-12,14,25H2,1-2H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	331	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human histamine H4 receptor in SK-N-MC cells assessed as forskolin-stimulated cAMP release preincubated for 10 mins before forsko...				Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z
					More data for this Ligand-Target Pair