BDBM50319284 (+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(1-methyltetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)propoxy)phenyl)-1H-benzo[d]imidazole::CHEMBL1084811

SMILES: CN1CCCC2CN(CCCOc3ccc(-c4nc5ccc(F)c(C)c5[nH]4)c(C)c3)CC12

InChI Key: InChIKey=RCRPDVSTEDUJHC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50319284 ((+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(1-methyl...) Show SMILES CN1CCCC2CN(CCCOc3ccc(-c4nc5ccc(F)c(C)c5[nH]4)c(C)c3)CC12 Show InChI InChI=1S/C26H33FN4O/c1-17-14-20(32-13-5-12-31-15-19-6-4-11-30(3)24(19)16-31)7-8-21(17)26-28-23-10-9-22(27)18(2)25(23)29-26/h7-10,14,19,24H,4-6,11-13,15-16H2,1-3H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z
					More data for this Ligand-Target Pair