BDBM50319291 (+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(1-methylhexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)propoxy)phenyl)-1H-benzo[d]imidazole::CHEMBL1085803

SMILES: CN1CCC2CN(CCCOc3ccc(-c4nc5ccc(F)c(C)c5[nH]4)c(C)c3)CC12

InChI Key: InChIKey=FGSBLNXBYOAEOJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50319291 ((+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(1-methyl...) Show SMILES CN1CCC2CN(CCCOc3ccc(-c4nc5ccc(F)c(C)c5[nH]4)c(C)c3)CC12 Show InChI InChI=1S/C25H31FN4O/c1-16-13-19(31-12-4-10-30-14-18-9-11-29(3)23(18)15-30)5-6-20(16)25-27-22-8-7-21(26)17(2)24(22)28-25/h5-8,13,18,23H,4,9-12,14-15H2,1-3H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	232	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z
					More data for this Ligand-Target Pair