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BDBM50319296 3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)-N-(pyridin-2-ylmethyl)propan-1-amine::CHEMBL1083159

SMILES: Cc1cc(OCCCNCc2ccccn2)ccc1-c1nc2ccc(F)c(C)c2[nH]1

InChI Key: InChIKey=DJVAZFOUJAETMH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319296   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50319296
PNG
(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-...)
Show SMILES Cc1cc(OCCCNCc2ccccn2)ccc1-c1nc2ccc(F)c(C)c2[nH]1
Show InChI InChI=1S/C24H25FN4O/c1-16-14-19(30-13-5-11-26-15-18-6-3-4-12-27-18)7-8-20(16)24-28-22-10-9-21(25)17(2)23(22)29-24/h3-4,6-10,12,14,26H,5,11,13,15H2,1-2H3,(H,28,29)
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human recombinant histamine H4 receptor


Bioorg Med Chem Lett 20: 3367-71 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.017
BindingDB Entry DOI: 10.7270/Q23J3D4Z
More data for this
Ligand-Target Pair