BDBM50319299 3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)-N-(pyrazin-2-ylmethyl)propan-1-amine::CHEMBL1082852

SMILES: Cc1cc(OCCCNCc2cnccn2)ccc1-c1nc2ccc(F)c(C)c2[nH]1

InChI Key: InChIKey=JVVAEDXXKBNOIX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50319299 (3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-...) Show SMILES Cc1cc(OCCCNCc2cnccn2)ccc1-c1nc2ccc(F)c(C)c2[nH]1 Show InChI InChI=1S/C23H24FN5O/c1-15-12-18(30-11-3-8-25-13-17-14-26-9-10-27-17)4-5-19(15)23-28-21-7-6-20(24)16(2)22(21)29-23/h4-7,9-10,12,14,25H,3,8,11,13H2,1-2H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z
					More data for this Ligand-Target Pair