BDBM50319306 CHEMBL1085403::N1-(3-(4-(5-tert-butyl-1H-inden-2-yl)-2-chlorophenoxy)propyl)-N1,N2,N2-trimethylethane-1,2-diamine
SMILES: CN(C)CCN(C)CCCOc1ccc(cc1Cl)-c1nc2ccc(cc2[nH]1)C(C)(C)C
InChI Key: InChIKey=TYTJKMWKUZYMSZ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H4 receptor (Homo sapiens (Human)) | BDBM50319306 (CHEMBL1085403 | N1-(3-(4-(5-tert-butyl-1H-inden-2-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor | Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z | |||||||||||
More data for this Ligand-Target Pair |