BDBM50319306 CHEMBL1085403::N1-(3-(4-(5-tert-butyl-1H-inden-2-yl)-2-chlorophenoxy)propyl)-N1,N2,N2-trimethylethane-1,2-diamine

SMILES: CN(C)CCN(C)CCCOc1ccc(cc1Cl)-c1nc2ccc(cc2[nH]1)C(C)(C)C

InChI Key: InChIKey=TYTJKMWKUZYMSZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50319306 (CHEMBL1085403 | N1-(3-(4-(5-tert-butyl-1H-inden-2-...) Show SMILES CN(C)CCN(C)CCCOc1ccc(cc1Cl)-c1nc2ccc(cc2[nH]1)C(C)(C)C Show InChI InChI=1S/C25H35ClN4O/c1-25(2,3)19-9-10-21-22(17-19)28-24(27-21)18-8-11-23(20(26)16-18)31-15-7-12-30(6)14-13-29(4)5/h8-11,16-17H,7,12-15H2,1-6H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z
					More data for this Ligand-Target Pair