BDBM50319427 CHEMBL1085627::N-{4-[2-(4-Acetylpiperazin-1-yl)ethoxy]-3-(1-methyl-1H-pyrazol-5-yl)phenyl}-3-fluorobenzamide

SMILES: CC(=O)N1CCN(CCOc2ccc(NC(=O)c3cccc(F)c3)cc2-c2ccnn2C)CC1

InChI Key: InChIKey=RLNQKFLDMDEXFL-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50319427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50319427 (CHEMBL1085627 | N-{4-[2-(4-Acetylpiperazin-1-yl)et...) Show SMILES CC(=O)N1CCN(CCOc2ccc(NC(=O)c3cccc(F)c3)cc2-c2ccnn2C)CC1 Show InChI InChI=1S/C25H28FN5O3/c1-18(32)31-12-10-30(11-13-31)14-15-34-24-7-6-21(17-22(24)23-8-9-27-29(23)2)28-25(33)19-4-3-5-20(26)16-19/h3-9,16-17H,10-15H2,1-2H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293 cells by scintillation counting				J Med Chem 53: 4412-21 (2010) Article DOI: 10.1021/jm100044a BindingDB Entry DOI: 10.7270/Q2KK9BZV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50319427 (CHEMBL1085627 | N-{4-[2-(4-Acetylpiperazin-1-yl)et...) Show SMILES CC(=O)N1CCN(CCOc2ccc(NC(=O)c3cccc(F)c3)cc2-c2ccnn2C)CC1 Show InChI InChI=1S/C25H28FN5O3/c1-18(32)31-12-10-30(11-13-31)14-15-34-24-7-6-21(17-22(24)23-8-9-27-29(23)2)28-25(33)19-4-3-5-20(26)16-19/h3-9,16-17H,10-15H2,1-2H3,(H,28,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293 cells by scintillation counting				J Med Chem 53: 4412-21 (2010) Article DOI: 10.1021/jm100044a BindingDB Entry DOI: 10.7270/Q2KK9BZV
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50319427 (CHEMBL1085627 | N-{4-[2-(4-Acetylpiperazin-1-yl)et...) Show SMILES CC(=O)N1CCN(CCOc2ccc(NC(=O)c3cccc(F)c3)cc2-c2ccnn2C)CC1 Show InChI InChI=1S/C25H28FN5O3/c1-18(32)31-12-10-30(11-13-31)14-15-34-24-7-6-21(17-22(24)23-8-9-27-29(23)2)28-25(33)19-4-3-5-20(26)16-19/h3-9,16-17H,10-15H2,1-2H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				J Med Chem 53: 4412-21 (2010) Article DOI: 10.1021/jm100044a BindingDB Entry DOI: 10.7270/Q2KK9BZV
					More data for this Ligand-Target Pair