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SMILES: CC(C)(C)CCc1nc(ccc1CNC(=O)Nc1cccc2[nH]ncc12)C(F)(F)F

InChI Key: InChIKey=RUQUDACHXCMJAG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319465   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50319465
PNG
(1-((2-(3,3-dimethylbutyl)-6-(trifluoromethyl)pyrid...)
Show SMILES CC(C)(C)CCc1nc(ccc1CNC(=O)Nc1cccc2[nH]ncc12)C(F)(F)F
Show InChI InChI=1S/C21H24F3N5O/c1-20(2,3)10-9-15-13(7-8-18(27-15)21(22,23)24)11-25-19(30)28-16-5-4-6-17-14(16)12-26-29-17/h4-8,12H,9-11H2,1-3H3,(H,26,29)(H2,25,28,30)
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n/an/a 5n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1

Bioorg Med Chem Lett 20: 3291-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.047
BindingDB Entry DOI: 10.7270/Q2B27VF7
More data for this
Ligand-Target Pair