BDBM50319474 CHEMBL1086519::rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-2-methyl-indol-1-yl]-acetic acid

SMILES: Cc1c(C2NS(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O

InChI Key: InChIKey=ZXPMFGVQZOZWQX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50319474 (CHEMBL1086519 | rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1...) Show SMILES Cc1c(C2NS(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C18H16N2O4S/c1-11-17(12-6-2-4-8-14(12)20(11)10-16(21)22)18-13-7-3-5-9-15(13)25(23,24)19-18/h2-9,18-19H,10H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay				Bioorg Med Chem Lett 20: 3287-90 (2010) Article DOI: 10.1016/j.bmcl.2010.04.046 BindingDB Entry DOI: 10.7270/Q26973QW
					More data for this Ligand-Target Pair