BDBM50319495 CHEMBL1082610::rac-{3-[2-(3,5-Dimethyl-isoxazol-4-ylmethyl)-1,1-dioxo-1lambda*6*-isothiazolidin-3-yl]-2-methyl-indol-1-yl}-acetic acid
SMILES: Cc1noc(C)c1CN1C(CCS1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12
InChI Key: InChIKey=CTQQSZNYLQIYHA-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G protein-coupled receptor 44 (Homo sapiens (Human)) | BDBM50319495 (CHEMBL1082610 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc. Curated by ChEMBL | Assay Description Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay | Bioorg Med Chem Lett 20: 3287-90 (2010) Article DOI: 10.1016/j.bmcl.2010.04.046 BindingDB Entry DOI: 10.7270/Q26973QW | |||||||||||
More data for this Ligand-Target Pair |