Found 6 hits for monomerid = 50319637 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Rho-associated protein kinase 2
(Homo sapiens (Human)) | BDBM50319637
(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)Show InChI InChI=1S/C18H16ClN3O2/c19-15-9-14-13(6-7-21-18(14)24)8-16(15)22-17(23)11-20-10-12-4-2-1-3-5-12/h1-9,20H,10-11H2,(H,21,24)(H,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of ROCK2 |
Bioorg Med Chem Lett 20: 3235-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z |
More data for this Ligand-Target Pair | |
Myotonin-protein kinase
(Homo sapiens (Human)) | BDBM50319637
(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)Show InChI InChI=1S/C18H16ClN3O2/c19-15-9-14-13(6-7-21-18(14)24)8-16(15)22-17(23)11-20-10-12-4-2-1-3-5-12/h1-9,20H,10-11H2,(H,21,24)(H,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of DMPK |
Bioorg Med Chem Lett 20: 3235-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z |
More data for this Ligand-Target Pair | |
Protein kinase N2
(Homo sapiens (Human)) | BDBM50319637
(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)Show InChI InChI=1S/C18H16ClN3O2/c19-15-9-14-13(6-7-21-18(14)24)8-16(15)22-17(23)11-20-10-12-4-2-1-3-5-12/h1-9,20H,10-11H2,(H,21,24)(H,22,23) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of Prkcl2 |
Bioorg Med Chem Lett 20: 3235-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z |
More data for this Ligand-Target Pair | |
Protein kinase C, epsilon
(Homo sapiens (Human)) | BDBM50319637
(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)Show InChI InChI=1S/C18H16ClN3O2/c19-15-9-14-13(6-7-21-18(14)24)8-16(15)22-17(23)11-20-10-12-4-2-1-3-5-12/h1-9,20H,10-11H2,(H,21,24)(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of Prkce |
Bioorg Med Chem Lett 20: 3235-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z |
More data for this Ligand-Target Pair | |
Cell division control protein 42 homolog
(Homo sapiens (Human)) | BDBM50319637
(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)Show InChI InChI=1S/C18H16ClN3O2/c19-15-9-14-13(6-7-21-18(14)24)8-16(15)22-17(23)11-20-10-12-4-2-1-3-5-12/h1-9,20H,10-11H2,(H,21,24)(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of CDc42 |
Bioorg Med Chem Lett 20: 3235-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z |
More data for this Ligand-Target Pair | |
Rho-associated protein kinase 1
(Homo sapiens (Human)) | BDBM50319637
(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)Show InChI InChI=1S/C18H16ClN3O2/c19-15-9-14-13(6-7-21-18(14)24)8-16(15)22-17(23)11-20-10-12-4-2-1-3-5-12/h1-9,20H,10-11H2,(H,21,24)(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of ROCK1 |
Bioorg Med Chem Lett 20: 3235-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z |
More data for this Ligand-Target Pair | |