BDBM50319639 CHEMBL1086517::N-(1-oxo-1,2-dihydroisoquinolin-6-yl)-2-phenylacetamide

SMILES: O=C(Cc1ccccc1)Nc1ccc2c(cc[nH]c2=O)c1

InChI Key: InChIKey=ZFTKMJDQCQPXDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50319639 (CHEMBL1086517 | N-(1-oxo-1,2-dihydroisoquinolin-6-...) Show SMILES O=C(Cc1ccccc1)Nc1ccc2c(cc[nH]c2=O)c1 Show InChI InChI=1S/C17H14N2O2/c20-16(10-12-4-2-1-3-5-12)19-14-6-7-15-13(11-14)8-9-18-17(15)21/h1-9,11H,10H2,(H,18,21)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 20: 3235-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z
					More data for this Ligand-Target Pair