BDBM50319640 CHEMBL1083117::N-(1-oxo-1,2,3,4-tetrahydrophthalazin-6-yl)-2-phenylacetamide

SMILES: O=C(Cc1ccccc1)Nc1ccc2C(=O)NNCc2c1

InChI Key: InChIKey=GPXGTVPWAQLMKR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50319640 (CHEMBL1083117 | N-(1-oxo-1,2,3,4-tetrahydrophthala...) Show SMILES O=C(Cc1ccccc1)Nc1ccc2C(=O)NNCc2c1 Show InChI InChI=1S/C16H15N3O2/c20-15(8-11-4-2-1-3-5-11)18-13-6-7-14-12(9-13)10-17-19-16(14)21/h1-7,9,17H,8,10H2,(H,18,20)(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 20: 3235-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z
					More data for this Ligand-Target Pair