BDBM50319651 CHEMBL1083116::N-(1-oxo-1,2-dihydroisoquinolin-6-yl)-1-phenylmethanesulfonamide

SMILES: O=c1[nH]ccc2cc(NS(=O)(=O)Cc3ccccc3)ccc12

InChI Key: InChIKey=INMMQIQAKXYUED-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50319651 (CHEMBL1083116 | N-(1-oxo-1,2-dihydroisoquinolin-6-...) Show SMILES O=c1[nH]ccc2cc(NS(=O)(=O)Cc3ccccc3)ccc12 Show InChI InChI=1S/C16H14N2O3S/c19-16-15-7-6-14(10-13(15)8-9-17-16)18-22(20,21)11-12-4-2-1-3-5-12/h1-10,18H,11H2,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 20: 3235-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z
					More data for this Ligand-Target Pair